DEFB106A
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Beta-defensin 106 is a protein that in humans is encoded by the DEFB106A gene.[1][2]
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 106, DEFB106A and DEFB106B, in head-to-head orientation. This gene, DEFB106A, represents the more centromeric copy.[2]
Function
The purified DEFB106 showed antimicrobial activity against Escherichia coli, Candida albicans and Staphylococcus aureus.[3]
References
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<references />, or <references group="..." />Further reading
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