Elixir

For other uses, see Elixir (disambiguation).

An elixir (from Arabic: الإكسير - al-'iksīr) is a clear, sweet-flavored liquid used for medicinal purposes, to be taken orally and intended to cure one's ills. When used as a pharmaceutical preparation, an elixir contains at least one active ingredient designed to be taken orally.

Types

Non-medicated elixirs

They are used as solvents or vehicles for the preparation of medicated elixirs: aromatic elixirs (USP), isoalcoholic elixirs (NF), or compound benzaldehyde elixirs (NF). Active ingredient dissolved in a solution that contains 15 to 50% by volume of ethyl alcohol.

Medicated elixirs

• Antihistaminic elixirs: used against allergy: chlorampheniramine maleate elixirs (USP), diphenhydramine HCl elixirs.
• Sedative and hypnotic elixirs: sedatives induce drowsiness, and hypnotics induce sleep: pediatric chloral hydrate elixirs.
• Expectorant: used to facilitate productive cough (cough with sputum): terpin hydrate elixirs.
• Miscellaneous: acetaminophen (paracetamol) elixirs, which are used as analgesics.

East Asian vitamin drinks

Daily non-alcoholic non-caffeinated 'vitamin drinks' have been popular in East Asia since the 1950s, with Oronamin from Otsuka Pharmaceutical perhaps the market leader. Packaged in brown light-proof bottles, these drinks have the reputation of being enjoyed by old men and other health-conscious individuals. Counterparts exist in South Korea and China.

Western energy drinks typically have caffeine and are targeted at a younger demographic, with colorful labels and printed claims of increased athletic / daily performance.

Composition

An elixir is a hydro-alcoholic solution of at least one active ingredient. The alcohol is mainly used to:

• Solubilize the active ingredient(s) and some excipients
• Retard the crystallization of sugar
• Preserve the finished product
• Provide a sharpness to the taste
• Aid in masking the unpleasant taste of the active ingredient(s)
• Enhance the flavor.

The lowest alcoholic quantity that will dissolve completely the active ingredient(s) and give a clear solution is generally chosen. High concentrations of alcohol give burning taste to the final product.

An elixir may also contain the following excipients:

• Sugar and/or sugar substitutes like the sugar polyols glycerol and sorbitol.
• Preservatives like parabens and benzoates and antioxidants like butylated hydroxytoluene (BHT) and sodium metabisulfite.
• Buffering agents
• Chelating agents like sodium ethylenediaminetetraacetic acid (EDTA)
• Flavoring agents and flavor enhancers
• Coloring agents

Storage

Elixirs should be stored in a tightly closed and light resistant container away from direct heat and sunlights.

See also

• Concoction
• Elixir of life
• Internal alchemy
• Energy drink
• Soft drink
• Panacea (medicine), mythological remedy that would cure all diseases
• Suspension (chemistry)
• Syrup
• Herbal tea
• Tincture, in which alcohol is the major solvent and the ingredient is often highly concentrated.
• List of topics characterized as pseudoscience