Aminopropionitrile
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| Names | |||
|---|---|---|---|
| IUPAC name
3-Aminopropanenitrile[1]
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| Other names
2-Cyanoethylamine[citation needed]
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| Identifiers | |||
151-18-8  |
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| 3DMet | B00834 | ||
| 1698848 | |||
| ChEBI | CHEBI:27413 |
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| ChemSpider | 21241485 |
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| EC Number | 205-786-0 | ||
| 600476 | |||
| Jmol 3D model | Interactive image | ||
| KEGG | C05670 |
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| MeSH | Aminopropionitrile | ||
| PubChem | 1647 | ||
| RTECS number | UG0350000 | ||
| UNII | 38D5LJ4KH2 |
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| Properties | |||
| C3H6N2 | |||
| Molar mass | 70.10 g·mol−1 | ||
| Appearance | Colourless liquid | ||
| Boiling point | 79 to 81 °C; 174 to 178 °F; 352 to 354 K at 2.1 kPa | ||
| Pharmacology | |||
| ATCvet code | QM01 | ||
| Related compounds | |||
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Related alkanenitriles
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Related compounds
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DBNPA | ||
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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| Infobox references | |||
Aminopropionitrile, also known as β-aminopropionitrile (BAPN), is an organic compound with both amine and nitrile functional groups. It is a colourless liquid. The compound occurs naturally and is of interest in the biomedical community.
Biochemical and medical occurrence
BAPN is the toxic constituent of peas from Lathyrus plants, e.g., lathyrus odoratus.[2] Lathyrism, a disease known for centuries, encompasses 2 distinct entities: a disorder of the nervous system (neurolathyrism) leading to limb paralysis, and a disorder of connective tissue, causing either bone deformity (osteolathyrism) or aortic aneurisms (angiolathyrim). BAPN causes osteolathyrism and angiolathyrism when ingested in large quantities."[3] It can cause osteolathyrism, neurolathyrism, and/or angiolathyrism.
It is an antirheumatic agent in veterinary medicine.
It has attracted interest as an anticancer agent.[4]
Production
Aminopropionitrile is prepared by the reaction of ammonia with acrylonitrile.[5]
See also
References
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- ↑ Chvapil, Milos "Inhibition of breast adenocarcinoma growth by intratumoral injection of lipophilic long-acting lathyrogens" Anti-Cancer Drugs 2005, volume 16, 201-210. doi:10.1097/00001813-200502000-00013
- ↑ Karsten Eller, Erhard Henkes, Roland Rossbacher, Hartmut Höke "Amines, Aliphatic" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2005. doi:10.1002/14356007.a02_001
