ABCA8

ATP-binding cassette, sub-family A (ABC1), member 8
Identifiers
Symbols	ABCA8 ; KIAA0822; MGC163152
External IDs	OMIM: 612505 MGI: 1351668 HomoloGene: 56029 GeneCards: ABCA8 Gene
Gene ontology Molecular function • ATP binding • ATPase activity, coupled to transmembrane movement of substances Cellular component • mitochondrial inner membrane • plasma membrane • integral component of membrane • intracellular membrane-bounded organelle Biological process • transport • lipid transport • metabolic process • transmembrane transport Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	10351	27404
Ensembl	ENSG00000141338	ENSMUSG00000020620
UniProt	O94911	Q8K440
RefSeq (mRNA)	NM_001288985	NM_013851
RefSeq (protein)	NP_001275914	NP_038879
Location (UCSC)	Chr 17: 68.87 – 68.96 Mb	Chr 11: 109.93 – 110 Mb
PubMed search	[1]	[2]

ATP-binding cassette sub-family A member 8 is a protein that in humans is encoded by the ABCA8 gene.

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The function of this protein has not yet been determined.

External links

• ABCA8 human gene location in the UCSC Genome Browser.
• ABCA8 human gene details in the UCSC Genome Browser.