CADPS2
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Calcium-dependent secretion activator 2 is a protein that in humans is encoded by the CADPS2 gene.[1]
Function
This gene encodes a member of the calcium-dependent activator of secretion (CAPS) protein family, which are calcium-binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells.[1]
Interactions
This gene interacts with brain-derived neurotrophic factor.
Clinical significance
Cadps2 has been linked to autism[2] and is in the 7q autism susceptibility locus (AUTS1). However, the finding of aberrant CADPS2 splicing was not found to be significant in another study.[3]
A knockout mouse model was found to have autistic-like characteristics.[2]
CADPS2 has been linked to human and mouse brain structure in two large genomic studies.[4][5]
References
<templatestyles src="Reflist/styles.css" />
Cite error: Invalid <references> tag; parameter "group" is allowed only.
<references />, or <references group="..." />Further reading
- Lua error in package.lua at line 80: module 'strict' not found.
- Lua error in package.lua at line 80: module 'strict' not found.
- Lua error in package.lua at line 80: module 'strict' not found.
- Lua error in package.lua at line 80: module 'strict' not found.
- Lua error in package.lua at line 80: module 'strict' not found.
- Lua error in package.lua at line 80: module 'strict' not found.
- Lua error in package.lua at line 80: module 'strict' not found.
- Lua error in package.lua at line 80: module 'strict' not found.
- Lua error in package.lua at line 80: module 'strict' not found.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
<templatestyles src="Asbox/styles.css"></templatestyles>
 |
This article on a gene on human chromosome 7 is a stub. You can help Wikipedia by expanding it. |
- ↑ 1.0 1.1 Lua error in package.lua at line 80: module 'strict' not found.
- ↑ 2.0 2.1 Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
