CAPN2

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Calpain-2 catalytic subunit is a protein that in humans is encoded by the CAPN2 gene.[1][2]

Function

The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported.[3]

Interactions

CAPN2 has been shown to interact with Bcl-2.[4]

References

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Further reading

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External links

  • The MEROPS online database for peptidases and their inhibitors: C02.002


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  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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