Central chromatolysis
From Infogalactic: the planetary knowledge core
File:Central chromatolysis - intermed mag - cropped.jpg
Micrograph of the anterior horn of the spinal cord showing motor neurons with central chromatolysis. H&E stain.
File:Central chromatolysis - nf - very high mag.jpg
Micrograph of the anterior horn of the spinal cord showing motor neurons with central chromatolysis. Neurofilament immunostain.
Central chromatolysis is a histopathologic change seen in the cell body of a neuron, where the chromatin and cell nucleus are pushed to the cell periphery, in response to axonal injury.[1][2] This response is associated with increased protein synthesis to accommodate for axonal sprouting. In addition to traumatic injuries, central chromatolysis may be caused by vitamin deficiency (pellagra[3]).
See also
References
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External links
- ↑ Neuropathology - Basic Reactions. University of Vermont. URL: http://www.uvm.edu/~jkessler/NP/neuropbr.htm. Accessed on: 1 January 2011.
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