Chebulagic acid
From Infogalactic: the planetary knowledge core
Identifiers | |
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23094-71-5 | |
ChEMBL | ChEMBL525240 |
Jmol 3D model | Interactive image |
PubChem | 12400 |
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Properties | |
C41H30O27 | |
Molar mass | 954.66 g/mol |
Vapor pressure | {{{value}}} |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references | |
Chebulagic acid is a benzopyran tannin and an antioxidant that has many potential uses in medicine.
It has been found to be immunosuppressive,[1] hepatoprotective,[2] and a potent alpha-glucosidase inhibitor,[3][4] a human gut enzyme useful in diabetic studies.
It has been shown to be active against Staphylococcus aureus and Candida albicans[5]
It is found in the plants Terminalia chebula, T. citrina and T. catappa.[6]
It is formed from geraniin through a glutathione-mediated conversion.[7]
References
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- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Sasidharan, J Enzyme Inhib Med Chem 27:578 2012 PMID 22512724
- ↑ Pham, Pharm Biol 2014 PMID 24635511
- ↑ [1]
- ↑ Chemopreventive effect of punicalagin, a novel tannin component isolated from Terminalia catappa, on H-ras-transformed NIH3T3 cells. Pin-Shern Chen and Jih-Heng Li, Toxicology Letters, Volume 163, Issue 1, 5 May 2006, Pages 44-53
- ↑ Glutathione-mediated conversion of the ellagitannin geraniin into chebulagic acid. Tanaka T, Kouno I and Nonaka G.I, Chemical and pharmaceutical bulletin, 1996, volume 44, no 1, pages 34-40, INIST:3003361
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