ELP2

Elongator acetyltransferase complex subunit 2
Elongator acetyltransferase complex subunit 2
Identifiers
Symbols	ELP2 ; SHINC-2; STATIP1; StIP
External IDs	OMIM: 616054 MGI: 1889642 HomoloGene: 6019 GeneCards: ELP2 Gene
Gene ontology
Molecular function	• RNA polymerase II core binding; • transcriptional repressor activity, RNA polymerase II transcription factor binding; • protein kinase binding; • histone binding;
Cellular component	• histone acetyltransferase complex; • cytoplasm; • transcription elongation factor complex; • transcriptional repressor complex; • Elongator holoenzyme complex;
Biological process	• negative regulation of transcription from RNA polymerase II promoter; • chromatin organization; • regulation of transcription from RNA polymerase II promoter; • transcription elongation from RNA polymerase II promoter; • regulation of JAK-STAT cascade;
	Sources: Amigo / QuickGO
Orthologs
Species	Human
Entrez	55250
Ensembl	ENSG00000134759
UniProt	Q6IA86
RefSeq (mRNA)	NM_001242875
RefSeq (protein)	NP_001229804
Location (UCSC)	Chr 18:; 36.13 – 36.18 Mb
PubMed search	[1]
	v; t; e;

Elongator complex protein 2 is a protein that in humans is encoded by the ELP2 gene.^[1]^[2]^[3]

Interactions

ELP2 has been shown to interact with STAT3^[2] and Janus kinase 1.^[2]

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