KRT85
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| Keratin 85, type II | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | KRT85 ; ECTD4; HB5; Hb-5; K85; KRTHB5; hHb5 | ||||||||||||
| External IDs | OMIM: 602767 MGI: 1859268 HomoloGene: 37603 GeneCards: KRT85 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 3891 | 406219 | |||||||||||
| Ensembl | ENSG00000135443 | ENSMUSG00000047641 | |||||||||||
| UniProt | P78386 | Q6IMF0 | |||||||||||
| RefSeq (mRNA) | NM_001300810 | NM_001003668 | |||||||||||
| RefSeq (protein) | NP_001287739 | NP_001003668 | |||||||||||
| Location (UCSC) | Chr 12: 52.36 – 52.37 Mb |
Chr 15: 101.43 – 101.44 Mb |
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| PubMed search | [1] | [2] | |||||||||||
Keratin, type II cuticular Hb5 is a protein that in humans is encoded by the KRT85 gene.[1][2][3]
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5.[3]
References
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