Lorena S. Beese
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| Lorena S. Beese | |
|---|---|
| Born | Lorena Sue Beese |
| Residence | Durham, North Carolina |
| Fields | Cancer Research, DNA replication, DNA mismatch repair |
| Institutions | Duke University School of Medicine |
| Alma mater | |
| Spouse | Homme Hellinga |
Lorena Beese is a James B. Duke Professor of Biochemistry at Duke University. She received her PhD in Biophysics from Brandeis University and did her postdoctoral work with Dr. Thomas A. Steitz at Yale University. In 2009 Dr. Beese was elected to the National Academy of Sciences.[1] Her research interests include structural biochemistry of DNA replication and human DNA mismatch repair and its connection to carcinogenesis. She is also interested in protein prenylation enzymes as targets for structure-based discovery of anticancer therapeutics and re-purposing of such therapeutics to treat pathogenic fungi and malaria.[2]
Research Interests
- Signal transduction
- Structure based drug design
- DNA replication
- DNA mismatch repair
- Observing enzymes in action
Selected Works
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- Beese, L., & Harvard University. (2005). Structure and mechanism of protein prenyltransferases: Analysis of a cancer therapeutic target.
- Beese, L., & Harvard University. (2005). Structures and mechanisms of a DNA polymerase: Nature's copier and spellchecker in action.
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References
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<references />, or <references group="..." />Categories:
- Pages with reference errors
- American biochemists
- American scientists
- Living people
- Year of birth missing (living people)
- Duke University faculty
- Brandeis University alumni
- People from Durham, North Carolina
- Place of birth missing (living people)
- Members of the United States National Academy of Sciences
- Women biochemists
- American women scientists
