Myotubularin
From Infogalactic: the planetary knowledge core
| Myotubularin-related | |||||||||
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| File:PDB 1m7r EBI.jpg
Structure of a phosphoinositide phosphatase.[1]
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| Identifiers | |||||||||
| Symbol | Myotub-related | ||||||||
| Pfam | PF06602 | ||||||||
| InterPro | IPR010569 | ||||||||
| SCOP | 1m7r | ||||||||
| SUPERFAMILY | 1m7r | ||||||||
| OPM protein | 1zvr | ||||||||
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Myotubularin domain represents a region within eukaryotic myotubularin-related proteins that is sometimes found with the GRAM domain IPR004182. Myotubularin is a dual-specific lipid phosphatase that dephosphorylates phosphatidylinositol 3-phosphate and phosphatidylinositol (3,5)-bi-phosphate.[2] Mutations in gene encoding myotubularin-related proteins have been associated with disease.[3]
Human proteins containing this domain
MTM1; MTMR1; MTMR10; MTMR11; MTMR12; MTMR2; MTMR3; MTMR4; MTMR6; MTMR7; MTMR8; MTMR9; SBF1; SBF2;
References
External links
This article incorporates text from the public domain Pfam and InterPro IPR010569
