PLXNA2
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Plexin-A2 is a protein that in humans is coded by the PLXNA2 gene.[1][2]
This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C.[2]
In some studies, the PLXNA2 gene is associated with schizophrenia.[3] and anxiety.[4]
References
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- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ 2.0 2.1 Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Gene Overview of All Published Schizophrenia-Association Studies for PLXNA2 - база данных SZGene, сайт Schizophrenia Research Forum
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