RNAI
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| RNAI | |
|---|---|
| 220px | |
| Predicted secondary structure and sequence conservation of RNAI | |
| Identifiers | |
| Symbol | RNAI |
| Rfam | RF00106 |
| Other data | |
| RNA type | Gene; antisense |
| Domain(s) | Bacteria |
| SO | 0000644 |
RNAI is a non-coding RNA that is an antisense repressor of the replication of some E. coli plasmids, including ColE1. Plasmid replication is usually initiated by RNAII,[1] which acts as a primer by binding to its template DNA. The complementary RNAI binds RNAII prohibiting it from its initiation role. The rate of degradation of RNAI is therefore a major factor in control of plasmid replication. This rate of degradation is aided by the pcnB (plasmid copy number B) gene product,[2] which polyadenylates the 3' end of RNAI targeting it for degradation by PNPase.[3]
References
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External links
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