TAF4B

TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
Identifiers
Symbols	TAF4B ; SPGF13; TAF2C2; TAFII105
External IDs	OMIM: 601689 MGI: 2152345 HomoloGene: 28266 GeneCards: TAF4B Gene
Gene ontology Molecular function • DNA binding • transcription factor activity, sequence-specific DNA binding • protein heterodimerization activity • NF-kappaB binding Cellular component • nucleoplasm • transcription factor TFIID complex • nucleolus • cytoplasm Biological process • regulation of transcription, DNA-templated • transcription from RNA polymerase II promoter • transcription initiation from RNA polymerase II promoter • transcription elongation from RNA polymerase II promoter • spermatogenesis • gene expression • viral process • oogenesis • positive regulation of stem cell proliferation Sources: Amigo / QuickGO
RNA expression pattern
File:PBB GE TAF4B gnf1h09648 s at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6875	72504
Ensembl	ENSG00000141384	ENSMUSG00000054321
UniProt	Q92750	G5E8Z2
RefSeq (mRNA)	NM_001293725	NM_001100449
RefSeq (protein)	NP_001280654	NP_001093919
Location (UCSC)	Chr 18: 26.23 – 26.39 Mb	Chr 18: 14.78 – 14.9 Mb
PubMed search	[1]	[2]

Transcription initiation factor TFIID subunit 4B is a protein that in humans is encoded by the TAF4B gene.

Function

TATA-binding protein associated factors (TAFs) participate, with TATA binding protein (TBP; MIM 600075), in the formation of the TFIID protein complex (see MIM 313650), which is involved in the initiation of gene transcription by RNA polymerase II (see MIM 180660).[supplied by OMIM]

Interactions

TAF4B has been shown to interact with RELA.