Template:PBB/5873

RAB27A, member RAS oncogene family
Identifiers
Symbols	RAB27A ; GS2; HsT18676; RAB27; RAM
External IDs	OMIM: 603868 MGI: 1861441 HomoloGene: 3069 GeneCards: RAB27A Gene
Gene ontology Molecular function • GTPase activity • protein binding • GTP binding • GDP binding • protein domain specific binding • myosin V binding Cellular component • photoreceptor outer segment • lysosome • late endosome • Golgi apparatus • apical plasma membrane • secretory granule • dendrite • secretory granule membrane • multivesicular body membrane • Weibel-Palade body • melanosome • extracellular exosome • exocytic vesicle Biological process • protein targeting • intracellular protein transport • exocytosis • vesicle docking involved in exocytosis • blood coagulation • protein secretion • positive regulation of gene expression • antigen processing and presentation • melanocyte differentiation • melanosome localization • melanosome transport • Rab protein signal transduction • multivesicular body organization • cytotoxic T cell degranulation • natural killer cell degranulation • cellular protein metabolic process • positive regulation of exocytosis • synaptic vesicle transport • positive regulation of phagocytosis • multivesicular body sorting pathway • complement-dependent cytotoxicity • positive regulation of regulated secretory pathway • positive regulation of reactive oxygen species biosynthetic process • positive regulation of constitutive secretory pathway • exosomal secretion Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	5873	11891
Ensembl	ENSG00000069974	ENSMUSG00000032202
UniProt	P51159	Q9ERI2
RefSeq (mRNA)	NM_004580	NM_001301230
RefSeq (protein)	NP_004571	NP_001288159
Location (UCSC)	Chr 15: 55.2 – 55.32 Mb	Chr 9: 73.04 – 73.1 Mb
PubMed search	[1]	[2]