Template:PBB/93986
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<templatestyles src="Module:Infobox/styles.css"></templatestyles>
Forkhead box P2
PDB
rendering based on 2a07.
Available structures
PDB
Ortholog search:
PDBe
,
RCSB
List of PDB id codes
2A07
,
2AS5
Identifiers
Symbols
FOXP2
; CAGH44; SPCH1; TNRC10
External IDs
OMIM
:
605317
MGI
:
2148705
HomoloGene
:
33482
GeneCards
:
FOXP2 Gene
Gene ontology
Molecular function
•
RNA polymerase II core promoter proximal region sequence-specific DNA binding
•
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
•
DNA binding
•
sequence-specific DNA binding transcription factor activity
•
protein binding
•
protein homodimerization activity
•
sequence-specific DNA binding
•
metal ion binding
•
protein heterodimerization activity
Cellular component
•
nucleus
Biological process
•
negative regulation of transcription from RNA polymerase II promoter
•
positive regulation of mesenchymal cell proliferation
•
transcription, DNA-templated
•
skeletal muscle tissue development
•
post-embryonic development
•
cerebellum development
•
caudate nucleus development
•
putamen development
•
cerebral cortex development
•
growth
•
vocal learning
•
camera-type eye development
•
negative regulation of transcription, DNA-templated
•
lung alveolus development
•
smooth muscle tissue development
•
righting reflex
•
positive regulation of epithelial cell proliferation involved in lung morphogenesis
Sources:
Amigo
/
QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species
Human
Mouse
Entrez
93986
114142
Ensembl
ENSG00000128573
ENSMUSG00000029563
UniProt
O15409
P58463
RefSeq (mRNA)
NM_001172766
NM_053242
RefSeq (protein)
NP_001166237
NP_444472
Location (UCSC)
Chr 7:
114.09 – 114.69 Mb
Chr 6:
14.9 – 15.44 Mb
PubMed
search
[1]
[2]
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:
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