Tridihexethyl

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Tridihexethyl
File:Tridihexethyl.svg
Systematic (IUPAC) name
3-cyclohexyl-N,N,N-triethyl-3-hydroxy-3-phenylpropan-1-aminium
Identifiers
CAS Number 60-49-1 YesY
ATC code A03AB08 (WHO)
PubChem CID: 20299
DrugBank DB00505 YesY
ChemSpider 19124 YesY
UNII 7HE50A367X YesY
ChEBI CHEBI:9701 YesY
ChEMBL CHEMBL1201354 N
Chemical data
Formula C21H36NO+
Molecular mass 318.517 g/mol
  • OC(c1ccccc1)(CC[N+](CC)(CC)CC)C2CCCCC2
  • InChI=1S/C21H36NO/c1-4-22(5-2,6-3)18-17-21(23,19-13-9-7-10-14-19)20-15-11-8-12-16-20/h7,9-10,13-14,20,23H,4-6,8,11-12,15-18H2,1-3H3/q+1 YesY
  • Key:NPRHVSBSZMAEIN-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

Tridihexethyl (which is commonly used as its chloride salt, tridihexethyl chloride) is an anticholinergic, antimuscarinic and antispasmodic drug. It may be used, usually in combination with other drugs, to treat acquired nystagmus[1] or peptic ulcer disease.[2] Many patients discontinue the drug because of unwanted side effects.

It is also known as Pathilon or Propethonum. [3]

References

  1. ↑ Effect of anticholinergic agents upon acquired nystagmus: A double-blind study of trihexyphenidyl and tridihexethyl chloride - Leigh et al. 41 (11): 1737 - Neurology
  2. ↑ DrugBank: DB00505 (Tridihexethyl)
  3. ↑ Tridihexethyl



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