Ureaplasma urealyticum infection
Ureaplasma urealyticum is a species in the genus Ureaplasma noted for its lack of a cell wall. It is found in about 70% of sexually active humans.[1] It can be found in cultures in cases of pelvic inflammatory disease and is transmitted through sexual activity or from mother to infant during birth.[2]
Clinical aspects
It had also been associated with a number of diseases in humans, including nonspecific urethritis, infertility,[3] chorioamnionitis, stillbirth, premature birth,[2] and, in the perinatal period, pneumonia, bronchopulmonary dysplasia[4] and meningitis.[5] U. urealyticum has been noted as one of the infectious causes of sterile pyuria.[6] It increases the morbidity as a cause of neonatal infections.[7]
Treatment
Doxycycline is the drug of choice, but azithromycin is also used as a five-day course rather than a single dose that would be used to treat Chlamydia infection;[8] streptomycin is an alternative, but is less popular because it must be injected. Penicillins are ineffective — U. urealyticum does not have a cell wall,[9] which is the drug's main target.[10][11]
References
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