ARG2
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Arginase, type II is an arginase protein that in humans is encoded by the ARG2 gene.[1]
Function
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II, this enzyme) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.
References
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<references />, or <references group="..." />Further reading
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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