Anti-actin antibodies

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schematic representation of antibody.

Anti-actin antibodies (AAA)[1] are found at increased frequency in certain autoimmune diseases and may be of some diagnostic value.

In coeliac disease anti-actin antibodies correlated with the level of intestinal damage.[2][3]

In autoimmune hepatitis anti-actin antibodies correlate with patterns of immune recognition,[4] the pattern of recognition was specific to a small percentage of auto-immune hepatitis type 1 or cryptogenic hepatitis patients.[5]

In gastric cancer anti-actin antibodies were elevated, along with other antibodies in severe disease with poor outcomes.[6]

References

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