Anti-p62 antibodies

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Autoantibody
Anti-p62
Autoantigen
Isoform
Nucleoporin 62kDA
Autoantigen gene NUP62
Affected organ(s) Bile duct
Associated
Disease(s)
Primary biliary cirrhosis
HLA associations DR2 (weak)

Anti-p62 antibodies (AP62A) are found in a primary biliary cirrhosis.[1] The p62 protein is also more frequent in Stage IV primary biliary cirrhosis and is prognostic for severe disease.[2][3] The autoantigen is the nucleoporin 62kDA protein.

References

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