Arachidonoyl serotonin
From Infogalactic: the planetary knowledge core
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Names | |
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IUPAC name
(5Z,8Z,11Z,14Z)-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)icosa-5,8,11,14-tetraenamide
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Other names
N-arachidonoyl-serotonin
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Identifiers | |
187947-37-1 ![]() |
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ChEMBL | ChEMBL191534 ![]() |
ChemSpider | 8202943 ![]() |
Jmol 3D model | Interactive image |
PubChem | 10027372 |
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Properties | |
C30H42N2O2 | |
Molar mass | 462.68 g·mol−1 |
Vapor pressure | {{{value}}} |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references | |
Arachidonoyl serotonin (N-arachidonoyl-serotonin, AA-5-HT) is an endogenous lipid signaling molecule. It was first described in 1998 as being an inhibitor of fatty acid amide hydrolase (FAAH).[1] In 2007, it was shown to have analgesic properties and to act as an antagonist of the TRPV1 receptor.[2] In 2011, it was shown to be present in the ileum and jejunum of the gastrointestinal tract and modulate glucagon-like peptide-1 (GLP-1) secretion.[3]
References
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