Delucemine

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Delucemine
Delucemine.png
Systematic (IUPAC) name
3,3-bis(3-fluorophenyl)-N-methylpropan-1-amine
Identifiers
CAS Number 186495-49-8 YesY
ATC code none
PubChem CID: 156421
ChemSpider 137745
UNII 124LSR3H2X YesY
ChEMBL CHEMBL2106165
Chemical data
Formula C16H17F2N
Molecular mass 261.3097 g/mol
  • CNCCC(C1=CC(=CC=C1)F)C2=CC(=CC=C2)F
  • InChI=1S/C16H17F2N/c1-19-9-8-16(12-4-2-6-14(17)10-12)13-5-3-7-15(18)11-13/h2-7,10-11,16,19H,8-9H2,1H3 N
  • Key:MUGNLPWYHGOJEG-UHFFFAOYSA-N N
 NYesY (what is this?)  (verify)

Delucemine (NPS-1506) is a drug which acts as an NMDA antagonist and a serotonin reuptake inhibitor, and has neuroprotective effects.[1][2] It was originally investigated for the treatment of stroke and in 2004 was studied as a potential antidepressant.[3][4][5]

Origin

The basic structure of Delucemine was based on argiotoxin 636, a NMDA antagonist isolated from the venom of the Araneid Argiope aurantia.[6][7][8]

See also

References

  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ NPS Pharmaceuticals Inc NPSP Quarterly Report
  4. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  5. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  6. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  7. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  8. ↑ Lua error in package.lua at line 80: module 'strict' not found.



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