Thymidylate synthase inhibitor
From Infogalactic: the planetary knowledge core
Thymidylate synthase inhibitors are chemical agents which inhibit the enzyme thymidylate synthase and have potential as an anticancer chemotherapy.[1] Five agents were in clinical trials in 2002: raltitrexed, pemetrexed, nolatrexed, ZD9331, and GS7904L.[2]
Examples include
- Raltitrexed, used for colorectal cancer since 1998
- Fluorouracil, used for colorectal cancer[3]
- BGC 945[4]
- OSI-7904L[5]
References
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