Zipeprol

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Zipeprol
Zipeprol.png
Systematic (IUPAC) name
1-methoxy- 3-[4-(2-methoxy- 2-phenylethyl)piperazin- 1-yl]- 1-phenylpropan- 2-ol
Clinical data
AHFS/Drugs.com International Drug Names
Legal status
Routes of
administration		 Oral
Identifiers
CAS Number 34758-83-3 N
ATC code R05DB15 (WHO)
PubChem CID: 36910
ChemSpider 33868 YesY
UNII G5MUV8139H YesY
KEGG D07390 YesY
Chemical data
Formula C23H32N2O3
Molecular mass 384.512 g/mol
  • OC(CN1CCN(CC1)CC(OC)c2ccccc2)C(OC)c3ccccc3
  • InChI=1S/C23H32N2O3/c1-27-22(19-9-5-3-6-10-19)18-25-15-13-24(14-16-25)17-21(26)23(28-2)20-11-7-4-8-12-20/h3-12,21-23,26H,13-18H2,1-2H3 YesY
  • Key:VSTNNAYSCJQCQI-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

Zipeprol is a centrally acting cough suppressant developed in France in the 1970s.[1] It is not an morphinan derivative (in contrast to codeine and dextromethorphan). Zipeprol acts as a local anaesthetic and has mucolytic, antihistamine and anticholinergic properties.[2]It is sold with several brand names such as Zinolta and Respilene. It is not available in the United States or Canada and has been discontinued in Europe. It is still available in some countries in Asia and South America.

Zipeprol has been misused in Korea, mainly for the hallucinations it produces. Such use has become an issue due to the seizures and various neurological side effects it causes at high dosages.[3]

References

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  1. ↑ Patent US 3718650, Mauvernay,RY, "New Derivatives of Substituted Piperazines", issued 1973-02-27 
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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