SNC-80

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SNC-80
SNC-80.svg
Systematic (IUPAC) name
4-[(R)-[(2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl](3-methoxyphenyl)methyl]-N,N-diethylbenzamide
Identifiers
CAS Number 156727-74-1 N
PubChem CID: 123924
IUPHAR/BPS 1611
ChemSpider 110453 YesY
ChEMBL CHEMBL13470 YesY
Synonyms SNC-80
Chemical data
Formula C28H39N3O2
Molecular mass 449.63 g/mol
  • O=C(N(CC)CC)c1ccc(cc1)[C@@H](N2C[C@H](N(C\C=C)C[C@@H]2C)C)c3cccc(OC)c3
  • InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m1/s1 YesY
  • Key:KQWVAUSXZDRQPZ-UMTXDNHDSA-N YesY
 NYesY (what is this?)  (verify)

SNC-80 is an opioid analgesic drug that selectively activates μ–δ opioid receptor heteromers[1] and is used in scientific research.[2] It was discovered in 1994.[3]

SNC-80 was the first non-peptide drug developed that was regarded as a highly selective agonist for the δ-opioid receptor.[4] It has been shown to produce useful analgesic,[5] antidepressant[6] and anxiolytic effects in animal studies,[7][8] but its usefulness is limited by producing convulsions at high doses,[9] and so SNC-80 is not used medically, although it is a useful drug in scientific research.

References

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