Etamivan

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Etamivan
Ethamivan.svg
Systematic (IUPAC) name
N,N-diethyl-4-hydroxy-3-methoxybenzamide
Clinical data
Trade names Analepticon
Identifiers
CAS Number 304-84-7
ATC code R07AB04 (WHO)
PubChem CID: 9363
DrugBank DB08989 YesY
ChemSpider 8996
UNII M44O63YPV9 YesY
KEGG D04080 YesY
Chemical data
Formula C12H17NO3
Molecular mass 223.268 g/mol
  • CCN(CC)C(=O)C1=CC(=C(C=C1)O)OC
  • InChI=1S/C12H17NO3/c1-4-13(5-2)12(15)9-6-7-10(14)11(8-9)16-3/h6-8,14H,4-5H2,1-3H3
  • Key:BQJODPIMMWWMFC-UHFFFAOYSA-N
  (verify)

Etamivan (INN) or ethamivan (USAN), trade name Analepticon, is a respiratory stimulant drug[1] related to nikethamide. It was mainly used in the treatment of barbiturate overdose[2] and chronic obstructive pulmonary disease,[3] but has now largely fallen into disuse.

References

  1. ↑ Hirsh K, Wang SC. Respiratory stimulant effects of ethamivan and picrotoxin. Journal of Pharmacology and Experimental Therapeutics. 1975 May;193(2):657-63.
  2. ↑ Wheeldon PJ, Perry AW. The use of ethamivan in the treatment of barbiturate poisoning. Canadian Medical Association Journal. 1963 Jul 6;89:20-2.
  3. ↑ Sproule BJ, Jans RL, Breitkreutz H, Mahon W. Effects of ethamivan in patients with chronic respiratory disease. Canadian Medical Association Journal. 1964 Dec 5;91:1203-8.


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