JZ-IV-10

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JZ-IV-10
16e chemical structure.png
Systematic (IUPAC) name
(+)-2-([(3R,4S)-1-methyl-4-(4-chlorophenyl)piperidin-3-yl]methylthio)-N-isopropylacetamide
Identifiers
CAS Number 807342-16-1 N
PubChem CID: 11291199
ChemSpider 9466185 N
Chemical data
Formula C18H27ClN2OS
Molecular mass 354.937 g/mol
  • Clc1ccc(cc1)[C@H]2CCN(C)C[C@@H]2CSCC(=O)NC(C)C
  • InChI=1S/C18H27ClN2OS/c1-13(2)20-18(22)12-23-11-15-10-21(3)9-8-17(15)14-4-6-16(19)7-5-14/h4-7,13,15,17H,8-12H2,1-3H3,(H,20,22)/t15-,17-/m1/s1 N
  • Key:GPNABXAHBDYHFE-NVXWUHKLSA-N N
 NYesY (what is this?)  (verify)

JZ-IV-10 is a piperidine derivative related to Cocaine which is a highly potent serotonin–norepinephrine–dopamine reuptake inhibitor (also called SNDRI, or triple reuptake inhibitor).[1] The eugeroic modafinil was used as a lead to fuel this compound's discovery.[2][3]

References

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  1. ↑ WO 2005041875 
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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