GPR32
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). G protein-coupled receptor 32, also known as GPR32 or the RvD1 receptor, is a human gene belonging to the rhodopsin-like subfamily of G protein-coupled receptors.[1] GPR32 is most closely related to the chemotaxic formyl peptide receptors.[2]
At least 5 members of the D series of resolvins (RvDs) viz., RvD1, AT-RVD1, RvD3, AT-RvD3, and RvD5, activate their target cells through this receptor; these results have led to naming GPR32 the RVD1 receptor (see Resolvin#Mechanisms of Action).[3][4][5] RvDs are metabolites of the omega-3 fatty acid, docosahexaenoic acid, that are implicated as contributing to the inhibition and resolution of a diverse range of inflammation and inflammation-related responses as well as in the healing of these inflammatory lesions in animals and humans (see Resolvin).
References
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Further reading
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- ↑ Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1660-5. doi: 10.1073/pnas.0907342107. Epub 2010 Jan 4.
- ↑ Cold Spring Harb Perspect Biol. 2014 Oct 30;7(2):a016311. doi: 10.1101/cshperspect.a016311. Review.PMID 25359497
- ↑ Am J Physiol Lung Cell Mol Physiol. 2015 May 1;308(9):L904-11. doi: 10.1152/ajplung.00370.2014. Epub 2015 Mar 13.