Gemazocine

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Gemazocine
Gemazocine structure.svg
Systematic (IUPAC) name
10-(cyclopropylmethyl)-1-ethyl-13,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2,4,6-trien-4-ol
Identifiers
CAS Number 54063-47-7
ATC code None
PubChem CID: 219096
ChemSpider 189916
ChEMBL CHEMBL2105066
Chemical data
Formula C20H29NO
Molecular mass 299.450 g/mol
  • Oc1ccc4c(c1)C2(C(C(N(CC2)CC3CC3)C4)(C)C)CC
  • InChI=1S/C20H29NO/c1-4-20-9-10-21(13-14-5-6-14)18(19(20,2)3)11-15-7-8-16(22)12-17(15)20/h7-8,12,14,18,22H,4-6,9-11,13H2,1-3H3
  • Key:AFZOCGNTFCGOEE-UHFFFAOYSA-N

Gemazocine (R-15,497), also known as cyclogemine, is a non-selective opioid antagonist of the benzomorphan class.[1][2][3] It may have partial agonist properties at some of the opioid receptors, such as at the kappa receptor (as it induces dysphoric effects in humans), but seems to be generally antagonistic in its actions.[4]

References

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