Nelivaptan

Nelivaptan
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Systematic (IUPAC) name
	(2S,4R)-1-[(3R)-5-chloro-1-(2,4-dimethoxyphenyl)sulfonyl-3-(2-methoxyphenyl)-2-oxo-indolin-3-yl]-4-hydroxy-N,N-dimethyl-pyrrolidine-2-carboxamide
Clinical data
Routes of; administration	Oral
Identifiers
CAS Number	439687-69-1
ATC code	none
PubChem	CID: 9895468
IUPHAR/BPS	2202
ChemSpider	8071134
UNII	3TY57MQ4OA
ChEMBL	CHEMBL582857
Chemical data
Formula	C30H32ClN3O8S
Molecular mass	630.11 g/mol
	InChI InChI=1S/C30H32ClN3O8S/c1-32(2)28(36)24-15-19(35)17-33(24)30(21-8-6-7-9-25(21)41-4)22-14-18(31)10-12-23(22)34(29(30)37)43(38,39)27-13-11-20(40-3)16-26(27)42-5/h6-14,16,19,24,35H,15,17H2,1-5H3/t19-,24+,30+/m1/s1 ; Key:NJXZWIIMWNEOGJ-WEWKHQNJSA-N ;
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Nelivaptan (INN^[1]), codenamed SSR-149,415, is a selective and orally active non-peptide vasopressin receptor antagonist selective for the V1b subtype.^[2] The drug had entered clinical trials for treatment of anxiety and depression.^[3] In July 2008, Sanofi-Aventis announced that further development of this drug had been halted.^[4]

References

SSR149415 at the US National Library of Medicine Medical Subject Headings (MeSH)

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