Teneligliptin

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Lua error in Module:Infobox at line 314: malformed pattern (missing ']'). Teneligliptin (INN; trade name Tenelia) is a pharmaceutical drug for the treatment of type 2 diabetes mellitus. It belongs to the class of anti-diabetic drugs known as dipeptidyl peptidase-4 inhibitors or "gliptins".[1]

Creation

It was created by Mitsubishi Tanabe Pharma and launched in September 2012 by both Mitsubishi Tanabe Pharma and Daiichi Sankyo in Japan.[2]

Licensing and use

Japan/Korea

It is approved for use in Japan, Korea and India. [3]

Pharmacology

Teneligliptin has unique J shaped or anchor locked domain structure because of which it has more potent inhibition of DPP 4 enzyme as compared to Sitagliptin and Vildagliptin.[citation needed]


Teneligliptin significantly controls glycemic parameters[clarification needed] with safety. No dose adjustment is required in renally impaired patients.[4]

References

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  1. Lua error in package.lua at line 80: module 'strict' not found.
  2. http://www.daiichisankyo.com/media_investors/media_relations/press_releases/detail/006054.html
  3. Lua error in package.lua at line 80: module 'strict' not found.
  4. Biochemical and Biophysical Research Communications, 2013, 434(2), 191-196