Aglepristone

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Aglepristone
Aglepristone.png
Systematic (IUPAC) name
(11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-[(1Z)-1-propen-1-yl]estra-4,9-dien-3-one
Identifiers
CAS Number 124478-60-0
ATC code G03XB90 (WHO)
PubChem CID: 14153279
ChemSpider 16736563
Chemical data
Formula C29H37NO2
Molecular mass 431.610 g/mol
  • C/C=C\[C@@]1(CC[C@@H]2[C@@]1(C[C@@H](C3=C4CCC(=O)C=C4CC[C@@H]23)c5ccc(cc5)N(C)C)C)O
  • InChI=1S/C29H37NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h5-7,9-10,15,17,24-26,32H,8,11-14,16,18H2,1-4H3/b15-5-/t24-,25+,26-,28-,29-/m0/s1
  • Key:RTCKAOKDXNYXEH-FWSJOHTJSA-N

Aglepristone (INN) (brand name Alizine; former code names RU-46534, RU-534) is a steroidal antiprogestin (progesterone receptor full antagonist) related to mifepristone which is marketed by Virbac in several European countries for use in veterinary medicine.[1][2][3] It is specifically used as an abortifacient in pregnant animals.[1][3][4] Aglepristone, similarly to mifepristone, also possesses some antiglucocorticoid activity.[citation needed]

References

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