Haloxazolam

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Haloxazolam
Haloxazolam structure.svg
Haloxazolam3d.png
Systematic (IUPAC) name
10-bromo-11b-(2-fluorophenyl)-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one
Clinical data
Trade names Somelin (JP)
AHFS/Drugs.com International Drug Names
Legal status
Routes of
administration		 Oral
Pharmacokinetic data
Metabolism Hepatic
Excretion Renal
Identifiers
CAS Number 59128-97-1 N
ATC code none
PubChem CID: 3563
DrugBank DB01476 YesY
ChemSpider 3442 YesY
UNII verifiedrevid = 461766568 M448L2V8XP verifiedrevid = 461766568 N
KEGG D01758 N
ChEMBL CHEMBL2104461 N
Chemical data
Formula C17H14BrFN2O2
Molecular mass 377.208 g/mol
  • Fc1ccccc1C42OCCN2CC(=O)Nc3c4cc(Br)cc3
  • InChI=1S/C17H14BrFN2O2/c18-11-5-6-15-13(9-11)17(12-3-1-2-4-14(12)19)21(7-8-23-17)10-16(22)20-15/h1-6,9H,7-8,10H2,(H,20,22) YesY
  • Key:XDKCGKQHVBOOHC-UHFFFAOYSA-N YesY
 NYesY (what is this?)

Haloxazolam (marketed in Japan under the brand name Somelin), is a drug which is a benzodiazepine derivative.[1][2][3] It has similar hypnotic properties as the benzodiazepine drugs triazolam, temazepam, and flunitrazepam and as such is indicated for the treatment insomnia.[4] A study in cats comparing estazolam and haloxazolam found that haloxazolam only affects gamma motor neurons, whereas estazolam affects both alpha and gamma motor neurons.[5]

See also

References

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