CD120
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Receptor subtypes
There are two variants of the receptor, each encoded by a separate gene:
- CD120a - TNFR1 - TNFR superfamily member 1A
- CD120b - TNFR2 - TNFR superfamily member 1B
TNFR1 is the receptor type responsible for mediation of TNF-alpha induced sickness behavior,[3] and is involved in neurotoxic processes.[4] Elevated levels of TNFR1 has been found in severe mental disorders.[5]
Signaling pathway
See also
References
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<references />, or <references group="..." />External links
- CD120a Antigen at the US National Library of Medicine Medical Subject Headings (MeSH)
- CD120b Antigen at the US National Library of Medicine Medical Subject Headings (MeSH)
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