Nafoxidine

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Nafoxidine
Nafoxidine.png
Systematic (IUPAC) name
1-[2-[4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)phenoxy]ethyl]pyrrolidine
Identifiers
CAS Number 1845-11-0
ATC code none
PubChem CID: 4416
IUPHAR/BPS 4263
ChemSpider 4263
UNII 4RIY10WM82 YesY
ChEMBL CHEMBL28211
Chemical data
Formula C29H31NO2
Molecular mass 425.562 g/mol
  • COC1=CC2=C(C=C1)C(=C(CC2)C3=CC=CC=C3)C4=CC=C(C=C4)OCCN5CCCC5

Nafoxidine (U-11,000A) is a non-steroidal antiestrogenic drug that has been investigated to treat advanced breast cancer.[1] It is structurally related to tamoxifen.

The drug is one of a series of similar structures invented at Upjohn. An earlier compound known as U-11,555 is related to Nafoxidine was found to cause photosensitivity in human volunteers.[2][3]

See also

References

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  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ http://www.sciencebase.com/serendipity_and_science.html
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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