CBFA2T3
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Protein CBFA2T3 is a protein that in humans is encoded by the CBFA2T3 gene.[1][2]
Function
The t(16;21)(q24;q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of this gene. In addition, this gene is a putative breast tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene, and a brefeldin A-sensitive association of RII-alpha protein with one of the isoforms has been demonstrated in the Golgi apparatus.[2]
Interactions
CBFA2T3 has been shown to interact with:
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References
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<references />, or <references group="..." />Further reading
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External links
- CBFA2T3 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it. |
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