HMGB2
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). High-mobility group protein B2 also known as high-mobility group protein 2 (HMG-2) is a protein that in humans is encoded by the HMGB2 gene.[1][2]
Function
This gene encodes a member of the non-histone chromosomal high-mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.[2]
References
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External links
- HMGB2 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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This article on a gene on human chromosome 4 is a stub. You can help Wikipedia by expanding it. |
