NFIB (gene)

Nuclear factor I/B
Identifiers
Symbols	NFIB ; CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B; NFI-RED; NFIB2; NFIB3
External IDs	OMIM: 600728 MGI: 103188 HomoloGene: 4087 GeneCards: NFIB Gene
Gene ontology Molecular function • RNA polymerase II core promoter proximal region sequence-specific DNA binding • RNA polymerase II transcription factor activity, sequence-specific DNA binding • transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding • RNA polymerase II transcription corepressor activity • DNA binding • double-stranded DNA binding Cellular component • nucleus • nucleoplasm • nucleolus • cerebellar mossy fiber Biological process • negative regulation of transcription from RNA polymerase II promoter • chondrocyte differentiation • DNA replication • transcription from RNA polymerase II promoter • glial cell differentiation • principal sensory nucleus of trigeminal nerve development • anterior commissure morphogenesis • hindbrain development • negative regulation of DNA binding • positive regulation of transcription from RNA polymerase II promoter • Clara cell differentiation • Type I pneumocyte differentiation • Type II pneumocyte differentiation • lung ciliated cell differentiation • commissural neuron axon guidance • negative regulation of mesenchymal cell proliferation involved in lung development • negative regulation of epithelial cell proliferation involved in lung morphogenesis Sources: Amigo / QuickGO
RNA expression pattern
File:PBB GE NFIB 209289 at tn.png
File:PBB GE NFIB 209290 s at tn.png
File:PBB GE NFIB 211467 s at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4781	18028
Ensembl	ENSG00000147862	ENSMUSG00000008575
UniProt	O00712	P97863
RefSeq (mRNA)	NM_001190737	NM_001113209
RefSeq (protein)	NP_001177666	NP_001106680
Location (UCSC)	Chr 9: 14.08 – 14.4 Mb	Chr 4: 82.29 – 82.71 Mb
PubMed search	[1]	[2]

Nuclear factor 1 B-type is a protein that in humans is encoded by the NFIB gene.

External links

• NFIB protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.