HNF1A
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). HNF1 homeobox A (hepatocyte nuclear factor 1 homeobox A), also known as HNF1A, is a human gene.[1][2]
The protein encoded by this gene is a transcription factor that is highly expressed in the liver and is involved in the regulation of the expression of several liver-specific genes.[3]
Clinical significance
HNF1A mutations can cause maturity onset diabetes of the young type 3, one of the forms of "monogenic diabetes",[2] as well as hepatocellular adenoma. HNF-1 protein is present in clear cell carcinoma of ovary [4][5]
Interactions
HNF1A has been shown to interact with:
See also
References
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This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it. |
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